Phylogenetic and Transcripts Profiling of Glucose Sensing Related Genes in Candida glabrata

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phylogenetic and transcripts profiling of glucose sensing related genes in candida glabrata

results comparative analysis of predicted amino acids in the phylogenetic tree showed high similarity between c. glabrata and s cerevisiae. besides, c. glabrata demonstrated the capability to grow in glucose levels as low as 0.01% in the spot dilution assay. in qrt-pcr analysis, differential expressions were observed in selected genes when c. glabrata was subjected to different glucose concentr...

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Phylogenetic and Transcripts Profiling of Glucose Sensing Related Genes in Candida glabrata

BACKGROUND The sensing mechanism of glucose in Saccharomyces cerevisiae is well studied. However, such information is scarcely found in other yeast species such as Candida glabrata. OBJECTIVES This study aimed to identify the glucose sensing pathway related genes of C. glabrata and to analyze the regulation pattern of these genes in response to different surrounding glucose concentrations thr...

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Candida glabrata, Friend and Foe

Candida glabrata is mostly good, but, at times, it is an opportunistic pathogen. Previously known as Torulopsis glabrata, it enjoyed a good reputation and was even present in starter cultures. Its haploid genome and lack of mating made it an attractive challenge for yeast genetics studies. However, more recently it has become better known due to its character as an emerging cause of candidiasis...

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Perinephric abscess is a rare complication of urinary tract infections, and the etiology is usually a gram negative bacillus. We report a case of Candida glabrata perinephric abscess in a patient with diabetes mellitus who had a recent episode of pyelonephritis that was treated with antibiotics. Percutaneous drainage and fluconazole treatment led to resolution of the infection. Yeast perinephri...

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azole-resistant Candida glabrata

Case report-Subjects-Three cases are described oflong-standing vaginal candidosis due to Candida glabrata. These had failed to respond to local and systemic antifungals. In each case the infecting strain appeared resistant to a range of azole drugs in vitro. Clinical course-Case one-This patient recovered following prolonged treatment with oral itraconazole in combination with oral and vaginal ...

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ژورنال

عنوان ژورنال: Jundishapur Journal of Microbiology

سال: 2015

ISSN: 2008-3645,2008-4161

DOI: 10.5812/jjm.25177